J Caring Sci. 2018;7(4):177-181.
doi: 10.15171/jcs.2018.027
PMID: 30607357
PMCID: PMC6311624
  Abstract View: 88
  PDF Download: 120

Original Research

Barriers of Drug Adherence among Patients with Epilepsy:  in Tertiary Care Hospital, South India

Ancy M Das 1, Lakshmi Ramamoorthy 1 * ORCiD, Sunil k. Narayan 2 ORCiD, Vaibhav Wadwekar 2 ORCiD

1 College of Nursing, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry (JIPMER), Puducherry, India
2 Departement of Neurology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry (JIPMER), Puducherry, India


Introduction: Epilepsy is a treatable and curable brain disorder. However major proportion of individuals with this disease in developing countries receives no treatment because of misunderstandings of the public. Other than that, poor adherence to ordered medication is considered the primary cause of drug therapy failure in epilepsy. This study conducted to assess the adherence pattern to antiepileptic regimen, among patients with epilepsy and to identify the clinical and patient-related factors contributing as barriers. Methods: A cross sectional survey design was used in 100 epilepsy patients in an Outpatient unit of tertiary care center. A Convenient sampling technique was used to enroll the patients who meet inclusion criteria. Structured interview with pre-tested questionnaire and eight item Morisky Medication Adherence Scale was used to collect the data. Descriptive and inferential statistics were used for analysis of data. Descriptive statistics (mean, standard deviation, frequency and percentages) were used to describe the clinical and demographic variables of study participants. The determinants of medication adherence were analyzed using Chi-Square test and independent student t- test. The analysis was done with SPSS 20th version. Results: Majority (71%) of patients were not adherent to antiepileptic treatment. Severity of seizure (indicated by the presence of seizure last year), medication frequency and complexity of treatment were found to have significant association with the Anti-Epileptic Drugs (AED) adherence status. Status of adherence is significantly associated with frequency of seizure/year and positive life style. Conclusion: As Medication adherence was observed to be low, services for adherence counseling and health educational interventions in the epilepsy clinics is recommended.

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Submitted: 19 Dec 2017
Revised: 03 Sep 2018
Accepted: 22 Oct 2018
First published online: 22 Oct 2018
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