J Caring Sci. 2021;10(2): 84-88.
doi: 10.34172/jcs.2021.016
  Abstract View: 40
  PDF Download: 74

Original Research

Comparing the Effects of Pulsatile and Continuous Flushing on Time and Type of Peripheral Intravenous Catheters Patency: A Randomized Clinical Trial

Seyed Javad Hosseini 1 ORCID logo, Fereshteh Eidy 2 ORCID logo, Majid Kianmehr 3 ORCID logo, Ali Asghar Firouzian 1 ORCID logo, Fatemeh Hajiabadi 4 ORCID logo, Mahmoud Marhamati 1 ORCID logo, Mahbobeh Firooz 1* ORCID logo

1 Department of Nursing, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran
2 Department of Biostatistics, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran
3 Department of Basic Sciences, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran
4 Department of Medical Surgical, Faculty of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran


Introduction: Peripheral intravenous catheters (PICs) patency techniques such as flushing are being developed. According to some studies, flushing can be used continuously or in pulsatile forms. This study aimed to compare the effects of pulsatile flushing (PF) and continuous flushing (CF) on time and type of PICs patency.
Methods: In this double-blind randomized clinical trial, 71 patients were randomly assigned into two groups of PF (n=35) and CF (n=36). The PF protocol was performed as successive injections of 1 mL normal saline (N/S) per second (sec) with a delay of less than 1 sec until the completion of 5 mL of solution. However, CF protocol was performed by injecting 5 mL N/S within 5 sec without any delay before and after each medicine administration. Data related to the time and type of PICs patency were collected using a patency checklist every 12 hours (h) up to 96 h. The statistical analysis was done by R statistical software (Version 3.5.1).
Results: The results showed that the number of PICs remaining open was not significantly different between PF and CF groups during 96 h. The highest number of PICs excluded from the study was related to the time of 96 h as a result of partial patency in the two groups.
Conclusion: There was no difference between CF and PF regarding the time and type of PICs patency. Thus, both techniques can be used to maintain the catheter patency.
Keywords: Pulsatile flow, Continuous flow, Peripheral Catheter, Vascular patency, Flushing
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Submitted: 18 Jan 2019
Revision: 27 Jul 2019
Accepted: 22 May 2021
ePublished: 23 May 2021
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