Logo-jcs
Journal of caring sciences. 9(1):39-45. doi: 10.34172/jcs.2020.007

Original Article

The Effect of Health Literacy Counselling on Self-Care in Women after Mastectomy: a Randomized Clinical Trial

Masoume Rastegar 1ORCID logo, Zohreh Mahmoodi 2, *ORCID logo, Sara Esmaelzadeh Saeieh 3ORCID logo, Nasibeh Sharifi 4ORCID logo, Kourosh Kabir 5ORCID logo
1Department of Midwifery, Student Research Committee, Medicine Faculty, Alborz University of Medical Sciences, Karaj, Iran
2Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj,
3Department of Midwifery, Medicine Faculty, Alborz University of Medical Sciences, Karaj, Iran
4Department of Midwifery, Nursing and Midwifery Faculty, Ilam University of Medical Sciences, Ilam, Iran
5Department of Community Medicine and Epidemiology, Medicine Faculty, Alborz University of Medical Sciences, Karaj, Iran
*Corresponding Author: PhD in social determinants of health. Email: zohrehmahmoodi2011@gmail.com

Abstract

Introduction: Breast cancer has a high prevalence, constituting a major cause of mortality in women around the world. Health literacy has a vital role in the self-care of chronic diseases such as cancer and is an essential element in the ability of each person to engage with health promotion. The aim of this study was to determine effect of health literacy counselling on self-care in women after mastectomy.

Methods: This study is a randomized, controlled, clinical trial carried out on 72 women with breast cancer after mastectomy in Fars province. The eligible women entered the study using convenience sampling and were then divided into an intervention and a control group through randomized blocks of four. Health literacy questionnaire and self-care questionnaire were distributed among the participants before, immediately after and three weeks following the intervention. Data analysis was performed in SPSS ver.13.

Results: The results showed no significant differences between the two groups in terms of their health literacy and self-care scores before the intervention (P=0.299 and 0.059). A comparison of the mean values showed a greater increase in the mean score of health literacy and score of self-care immediately and three weeks after the intervention in the intervention group compared to the control group. Also, the mean score of the dimensions of self-care in chemotherapy increased over time in the intervention group.

Conclusion: The findings of this study confirm the higher effectiveness of counseling with a health literacy approach on overall self-care in chemotherapy and all its dimensions.

Keywords: Counselling, Mastectomy, Health literacy, Self-care, Clinical trial

Copyright

© 2020 The Author(s).
This work is published by Journal of Caring Sciences as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.


Introduction

Malignancies are the most important health problem in the world. Breast cancer is a highly common malignancy in women, affecting one out of every eight women, which might lead to mortality.1 This cancer is almost specific to women, and more than 99% of those affected are female; however, men are not exempted, and 1% of all breast cancer diagnoses and less than 0.01% of breast cancer-related deaths occur in men.2 Although breast cancer has the lowest incidence rate in Iran compared to other Asian countries, the rise in its prevalence over the last four decades has made the disease a very frequent malignancy in women in Iran.3

Breast cancer treatment varies, depending on its severity. The main treatment involves breast surgery in the form of lumpectomy or mastectomy followed by chemotherapy.4 Chemotherapy is an important systemic therapy with an increasing use in the treatment of cancer. This technique is the first choice for controlling and preventing the progress of cancer, but has severe side-effects that occur due to physiological changes in the body organs and systems.5 The complications of chemotherapy include nausea and vomiting, fatigue, hanges in palate, alopecia, sexual dysfunction, memory loss, attention problems and inability to adhere to chemotherapy.6-8 Chemotherapy may thus have the greatest effect on patients’ quality of life and disrupt their physical, psychological, social and spiritual well-being.9 Finding a way to reduce the severity of these complications is very important. Self-care is one of the key ways for reducing these problems.10

Self-care includes regular training and supportive interventions that the health care team offers to enhance the patients' adeptness and trust in managing their health problems and consists of constant monitoring of the existing problems, tracking their progress, goal-setting and providing support for solving the problems.11

Greater attention is paid to the concept of self-care in the modern world due to humans’ need for maintaining and promoting their health, recovery, lack of health care facilities and hygiene, lack of adequate and equal access to facilities in all parts of the society and the substantial costs of health care services.12

Health literacy has a vital role in the self-care of chronic diseases such as cancer. For the daily management of a chronic or even a long-term disease, people must first have an understanding of their own health information.13 Yet, 25% of patients cannot properly obtain and process essential information about their own health verbally and in writing to make appropriate decisions, and this deficiency has made health literacy a major concern with regard to cancer.14 Health literacy should not only be considered a personal attribute, but also a key health determinant across the community.

Health literacy plays a vital role in the self-care of chronic diseases, including cancer, and is an essential element in the ability of each person to engage with health promotion and prevention activities. Therefore, considering the high rate of breast cancer in Iran, on the one hand, and the direct impact of this disease on the health of the family and society, on the other, research on health literacy and self-care can lead to the discovery and identification of pathways which can improve the well-being of patients. Considering the importance of attention to the impact of health literacy for promoting health behaviors and the need to pay attention to the care methods used for women with breast cancer, and also the role of obstetricians as the main health care providers in women.The aim of this study was to investigate the effect of health literacy counselling on self-care in women after mastectomy.


Materials and methods

The ethics committee of Alborz University of Medical Sciences approved this research in a meeting held on March 4, 2017 (abzums.rec.1395.144), and the project was then registered at the Iranian Registry of Clinical Trials (IRCT2017022327728N5). Written informed consent was obtained from all the subjects.

The current randomized clinical trial was conducted in parallel on 72 eligible women presenting to select health centers of Fars Province in 2017.

Based on the difference between two means equation and similar studies, and taking into account a standard deviation of 10 for self-care, a difference of 7 points and a potential sample loss of 10%, the sample size was set as 32 per group. The participants were selected from among women with breast cancer undergoing mastectomy in select health centers of Fars Province.

The study inclusion criteria consisted of: being of Iranian nationality; being a woman with breast cancer who has undergone mastectomy; having received one session of chemotherapy; having no other underlying diseases; and being willing to participate in the study.

The study exclusion criteria consisted of not attending at least two sessions of the counselling provided; and not having filled out the questionnaires or having returned incomplete ones.

The data were collected, using the Iranian Health Literacy Questionnaire (IHLQ),15 a researcher-made self-care in chemotherapy questionnaire, and a self-reporting checklist of personal-demographic details. The IHLQ contains 66 items with nine subsets, including: 1) access to health information sources; 2) application of sources; 3) reading literacy; 4) comprehension; 5) the ability to evaluate the content of health resources; 6) decision-making and communication skills; 7) health knowledge; 8) personal empowerment; and 9) social empowerment. In 2014, Haghdoost et al., confirmed the validity and reliability of this tool.15

Given the lack of a questionnaire for self-care in chemotherapy in Iran, the researchers designed a questionnaire using the available relevant questionnaires,16,17 self-care book for chemotherapy of National Cancer Institute,18 the existing self-care instructions for chemotherapy (Motahari Chemotherapy Clinic in Shiraz ) and expert opinions. The developed questionnaire contained five dimensions, including: 1(digestive health; 2) physical, psychological and mental health; 3)skin health;4) self-care knowledge; and5 sexual health. Validity of the designed instruments was determined using face validity, content validity. Validity has both qualitative and quantitative aspects. The qualitative aspects are conceptual. The quantitative aspects are numerical for face validity, ten patients filled out the form, and for assessing the content validity, 10 faculty members in reproductive health, obstetrics/gynecology and oncology were asked to comment on the items. The reliability of the tool was assessed, using the Cronbach's alpha test. On 50 women who present in center for getting service

For sampling, the researcher visited Motahari Chemotherapy Clinic in Fars Province, and selected eligible patients through convenience sampling and briefed them on the research aims and got their written consents then if they satisfied, using permuted block randomization to randomly allocate a participant to a control group(routine counseling on mastectomy and chemotherapy based on the center’s guidelines and the same educational self-care package given to the intervention group), while maintaining a balance across intervention groups(routine counseling on mastectomy and chemotherapy based on the center’s guidelines plus counseling for health literacy on self-care). Each “block” has a specified number of randomly ordered treatment assignments.

Six 1.30-hour sessions were held for both the intervention and control groups. To avoid the two groups’ coming into contact with each other, the counseling sessions were held on different days in groups of three to five. The subjects discussed in the intervention group included: session 1) group members and the leader getting to know one another, creating a positive rapport, announcing the group rules and motivating the members to actively participate in the sessions and be on time, giving further details on the disease, learning of the individual's feelings about the disease, and their understanding of the effect of the disease on their body. Session 2) providing counseling on health-related concepts, conveying basic information and getting to know the individual's thoughts about personal health and self-care, learning of their self-care problems and teaching ways to deal with them. Session 3) conveying basic information and getting to know the individual's thoughts about sexual health, hearing of their sexual problems and emphasizing the need to identify, prevent and deal with these problems. Session 4) conveying basic information and getting to know the individual's thoughts about mental health (stress and depression), its symptoms and consequences, and emphasizing the need to identify, prevent and deal with them, understanding concepts related to communication skills, and understanding the effect of family and social support. Session 5) conveying basic information and getting to know the individual's thoughts about the complications of the treatments provided, emphasizing the need to identify, prevent and deal with them, and teaching them about the breast cancer care services available to them. Session 6) going over the subjects discussed, practicing the skills taught, answering questions, and getting feedback about the content of the sessions held. At the beginning of the sessions, right after the end of the sessions, and three weeks later, both groups filled out the IHLQ and the self-care in chemotherapy questionnaire. The researcher followed up the participants on the phone during the process. A total of 72 women entered the study, but eight were excluded in the process, including three participants from the intervention group for not completing the counseling sessions and one for not presenting to the center at the agreed-upon time, and four were excluded from the control group as well, because they did not wish to attend the sessions. The study was completed with 64 participants. shows the Consolidated Standards of Reporting Trials (CONSORT) flow diagram of the study participants.

jcs-9-39-g001
Figure 1. Flow chart of the study

SPSS Ver. 13 (version 13.0, Chicago, IL, USA) and Mann-Whitney’s test, the Chi-square test and Repeated Measurement ANOVA were used for data analysis.


Results

This study was completed with participation of 64 women with breast cancer after mastectomy who had been to the first session of their chemotherapy. Mean age and standard deviation of sample was 41.47(8.72). After using Man-Whitney’s test to ensure the normality of the assessed variables, and the Chi-square test were carried out and did not show a significant difference between the two groups with regard to mean age, education, occupation and income; in other words, the two groups matched in terms of these variables (Table 1).

Table 1. Issue distribution of women’s demographic characteristics of breast cancer
VariableGroupP-value
Control
N (%)
Intervention
N (%)
Patient's age 0.90
<303(8.33)7(19.44)
30-4011(30.55)8(22.22)
>4022(61.12)21(58.34)
Patient education 0.59
Illiterate4(11.11)4(11.17)
Less than a diploma20(55.56)18(50)
Diploma10(27.77)9(25)
Bachelor2(5.56)5(13.8)
Job status 0.16
Housekeeper17(47.22)19(52.8)
Retired7(19.44)4(11.11)
Unemployed3(8.33)3(8.33)
Employed3(8.33)5(13.88)
Temporary employed6(16.68)5(13.88)
Income 0.21
Weak25(69.40)21(58.33)
Average9(25)10(27.77)
Good 2(5.6)5(13.9)
Nationality 0.99
Fars27(75)26(72.17)
Turkish2(5.50)3(8.33)
Lor7(19.5)7(19.5)

Chi-square test, was used for data analysis

In the quantitative face validity assessment, the impact score was calculated as 2.2 to 5 for all the items, and since these values were greater than 1.5, all the items were kept. In the content validity assessment, the items’ CVR, ranging from 0.8 to 1, was greater than 0.62 and their CVI which ranged from 0.76 to 1 was greater than 0.7, leading to no items being eliminated, as a result. The Cronbach's alpha internal consistency of the researcher-made questionnaire was calculated as 0.83, and the tool was thus approved for use in extensive research.

The results showed no significant differences between the two groups in terms of their health literacy and self-care scores before the intervention (P=0.299 and 0.059). In other words, at baseline, the two groups had similar health literacy and self-care knowledge. In the intervention group, the mean score of the dimensions of health literacy increased immediately and three weeks after the intervention. The two groups differed significantly in terms of the overall mean scores of health literacy over time (P<0.001). A comparison of the mean values showed a greater increase in the mean score of health literacy immediately and three weeks after the intervention in the intervention group compared to the control group, which is indicative of the effectiveness of counseling in the intervention group (Table 2).

Table 2. Comparison of mean score of general dimensions of health literacy in two groups before, immediately and three weeks after intervention in women with breast cancer
Health literacy dimensionsBefore intervention
Mean(SD)
After intervention
Mean(SD)
3 Weeks after intervention Mean(SD)Statistical indicators*
Access to information resources P<0.001,F=46.55
Control group1.87( 0.16)2.06( 0.18)2.03( 0.18)
Intervention group1.94( 0.14)3.129( 0.12)2.37( 0.18)
Information acquisition P<0.001,F=26.03
Control group2.03( 0.12)2.34( 0.17)2.15(0.12)
Intervention group2.37( 0.17)3.31( 0.2)3.06( 0.19)
Ability to read P<0.001,F=114.69
Control group2.91(0.32)3.87( 0.35)3.56( 0.33)
Intervention group4.47(0.63)9.56( 0.47)9.12( 0.44)
Ability to understand P<0.001,F=107.86
Control group8.69( 0.29)9.28( 0.27)8.69( 0.28)
Intervention group9.37( 0.8)14.47( 0.67)13.31( 0.64)
Judgment and evaluation P<0.001,F=81.20
Control group4.56( 0.23)5.03( 0.21)4.75( 0.2)
Intervention group5.62( 0.60)9.12( 0.41)8.72( 0.37)
Ability to make decisions P<0.001,F=34.88
Control group3.34( 0.17)3.69( 0.18)3.12( 0.2)
Intervention group4.12( 0.32)11.75( 0.27)10.81(0.27)
Individual empowerment P<0.001,F=12.65
Control group3.82( 0.49)4.12(0.18)3.99( 0.61)
Intervention group2.12.(0.45)9.65( 0.38)9.11( 0.55)
Knowledge P<0.001,F=92.41
Control group4.25( 0.28)4.80( 0.81)4.4( 0.2)
Intervention group3.71( 0.18)8.52(0.43)7.54( 0.35)
Social empowerment P<0.001,F=57.17
Control group1.25( 0.17)1.43( 0.18)1.16( 0.15)
Intervention group2.19( 0.32)4.78( 0.27)4.5(0.25)
Total health literacy P<0.001,F=25.42
Control group1.25(0.17)1.43( 0.18)1.16( 0.15)
Intervention group2.19( 0.32)4.78( 0.27)4.5( 0.25)

Repeated Measurement was used for data analysis, *All dimensions were statistically significant

In the current study, the intervention and control groups showed significant differences in terms of the mean overall score of self-care over time (P<0.001). A comparison of the mean values showed a greater increase in the mean score of self-care immediately and three weeks after the intervention in the intervention group compared to the control group. Also, the mean score of the dimensions of self-care in chemotherapy increased over time in the intervention group (P<0.001), which indicates the effectiveness of counseling in the intervention group (Table 3).

Table 3. Comparison of mean scores of self-care dimensions in two groups before, immediately and three weeks after intervention in women with breast cancer
Self-care dimensionsBefore intervention
Mean(SD)
After intervention
Mean(SD)
3 Weeks after intervention
Mean(SD)
Statistical indicators*
Digestive health P<0.001,F=118.97
Control group10.62( 0.41)10.81( 0.37)10.03( 0.34)
Intervention group9.72( 0.76)17.82( 0.49)16.62( 0.43)
Physical-mental-psychological health P<0.001,F=129.21
Control group9.69( 0.49)10.21( 0.48)9.81( 0.47)
Intervention group9.78( 0.70)17.87( 0.47)16.93(0.43)
Skin health P<0.001,F=41.95
Control group0.84( 0.15)1.03( 0.14)0.9(0.47)
Intervention group1.44( 0.17)2.56( 0.14)2.5( 0.13)
Self-care knowledge P<0.001,F=214.15
Control group20.56( 0.55)21.69( 0.56)20.9(0.52)
Intervention group19.28( 0.99)32.81( 0.57)31.41( 0.51)
Sexual health P<0.001,F=509.52
Control group2.47( 0.27)2.93( 0.23)2.69( 0.22)
Intervention group1.37( 0.27)9.75( 0.27)9.34( 0.27)
Total self-care P<0.001, F=405.23
Control group44.19( 0.94)46.69( 0.93)44.34( 0.84)
Intervention group41.59(2.16)80.81( 1.16)76.81(1.08)

Repeated measurement was used for data analysis,*All dimensions were statistically significant


Discussion

Breast cancer is a remarkable exception that shows the positive slope of health education.19 Following their diagnosis, breast cancer patients have a number of important treatment decisions to make. Accurate, reliable and comprehensible information is vital to these patients.20 Access to health information, treatment literacy and the ability to understand this information are vital to the individual's health management.21 Addressing these information needs helps cancer patients gain control of their condition and enhances their participation and self-care.22

According to the results obtained, the two groups had no significant differences before counseling in terms of their self-care score; in other words, the two groups were matching in terms of their self-care knowledge at baseline, but after the intervention, the scores obtained in the digestive health, physical, psychological and mental health, skin health, self-care knowledge, sexual health and general self-care dimensions showed a greater increase in the intervention group compared to the controls immediately and three weeks after counselling.

Since the two groups had been matched in this regard before the intervention, the result is indicative of the role and effectiveness of counseling and the presence of a counselor in promoting self-care compared to when only an educational package is offered. In line with the present findings, many studies have pointed to the positive effects of self-care interventions on the management of symptoms in patients with cancer.23-25 In a study entitled "The effectiveness of a self-care intervention to improve cancer pain management", Miaskofski et al., found that the pain intensity score reduced significantly in the intervention group compared to the controls against the baseline score, and concluded that using a psychological intervention within a self-care framework can improve the management of cancer pain.26 Also, in a randomized trial entitled “Evidence suggests that a self-management program can reduce hospital stay and improve health in patients with chronic diseases", Lorig et al., found an improvement in health behaviors and the health status of patients receiving treatment compared to the controls, and a reduction was observed in the frequency of admission and the number of hospitalization days.27

The findings of this latter study agree with the results obtained in the study by Haghighi et al., on the effect of group counseling on depression in patients with breast cancer. They found a significant reduction in the depression score in the intervention group following therapy, but the level of depression showed no changes in the control group.28

In the current study, the two groups did not have significantly different health literacy scores before the intervention; that is, the two groups were matching in terms of their health literacy. After the intervention, however, a greater increase was observed in the mean health literacy score of the intervention group compared to the controls immediately and three weeks after the intervention. Since the groups were matched for demographic characteristics and health literacy, these results indicate the role and effectiveness of counseling in the presence of a midwife counselor on health literacy in patients after mastectomy. Many studies have addressed the effect of health literacy on diseases; for example, in their study entitled "Health literacy and cancer communication", Davis et al., argued that interventions addressing the subject of health literacy offer a great opportunity for achieving the goal of controlling cancer.29

A multivariate analysis conducted by Gazmararian et al., entitled "Health literacy and knowledge of chronic disease" showed that health literacy has an independent relationship with knowledge of diseases. They found massive opportunities for improving the patients' knowledge about their chronic diseases and concluded that attempts should be made to increase the patients’ health literacy skills.30

The strengths of this research are that the two groups were similar with respect to confounding personal-demographic variables, including age, education, occupation and income and the main variables health literacy and self-care, which could have otherwise affected the results. The results obtained are thus assumed to be independent of the effect of these variables. Attempts were made in this study to match the participants, but the various educational media existing today and their potential effects may constitute a limitation of this research.


Conclusion

The findings of this study confirm the higher effectiveness of counseling with a health literacy approach in the presence of a midwife counselor compared to educational packages offered with routine counseling on overall self-care in breast cancer related chemotherapy and all of its dimensions. Providing counseling with the help of experts such as obstetricians as the main health care providers in women can substantially help increase health literacy and subsequently improve self-care in chemotherapy. It is suggested that self-care education be provided to patients' family during this period, which will further support patients.


Acknowledgments

Hereby, the researcher would like to express her gratitude to the Research Deputy of Alborz University of Medical Sciences for funding this study and people who helped us in this study.


Ethical issues

None to be declared.


Conflict of interest

The authors declare no conflict of interest in this study.


Research Highlights

What is the current knowledge?

Breast cancer is a highly common malignancy in women, affecting one out of every eight women, which might lead to mortality.

What is new here?

Counseling with a health literacy approach has effectiveness on overall self-care in chemotherapy and all its dimension.


Author’s contributions

All the authors contributed to the conception and design of the study. ZM and MR wrote the first draft of the paper. NSh and SE revised the manuscript. KK and ZM have analyzed the research data. All authors read and approved the final manuscript.


References

  1. Wapnir IL, Price KN, Anderson SJ, Robidoux A, Martín M, Nortier JW. Efficacy of chemotherapy for ER-negative and ER-positive isolated locoregional recurrence of breast cancer: final analysis of the CALOR trial. J Clin Oncol 2018; 36(11):1073-9. doi: 10.1200/JCO.2017.76.5719 [Crossref]
  2. Lukong KE. Understanding breast cancer–the long and winding road. BBA Clin 2017; 27(7):64-7. doi: 10.1016/j.bbacli.2017.01.001 [Crossref]
  3. Goya MM. . Iranian annual cancer registration report 2003 2005.
  4. Ahern T, Gardner A, Courtney M. Exploring patient support by breast care nurses and geographical residence as moderators of the unmet needs and self-efficacy of Australian women with breast cancer: results from a cross-sectional, nationwide survey. Eur J Oncol Nurs 2016; 23(1):72-80. doi: 10.1016/j.ejon.2016.05.001 [Crossref]
  5. Barrou J, Bannier M, Cohen M, Lambaudie E, Gonçalves A, Bertrand P. Pathological complete response in invasive breast cancer treated by skin sparing mastectomy and immediate reconstruction following neoadjuvant chemotherapy and radiation therapy: comparison between immunohistochemical subtypes. Breast 2017; 32(1):37-43. doi: 10.1016/j.breast.2016.12.014 [Crossref]
  6. Hosseini M, Tirgari B, Forouzi MA, Jahani Y. Guided imagery effects on chemotherapy induced nausea and vomiting in Iranian breast cancer patients. Complement Ther Clin Pract 2016; 25(1):8-12. doi: 10.1016/j.ctcp.2016.07.002 [Crossref]
  7. O’Regan P, Hegarty J. The importance of self-care for fatigue amongst patients undergoing chemotherapy for primary cancer. Eur J Oncol Nurs 2017; 28(1):47-55. doi: 10.1016/j.ejon.2017.02.005 [Crossref]
  8. Hutchinson AD, Hosking JR, Kichenadasse G, Mattiske JK, Wilson C. Objective and subjective cognitive impairment following chemotherapy for cancer: a systematic review. Cancer Treat Rev 2012; 38(7):926-34. doi: 10.1016/j.ctrv.2012.05.002 [Crossref]
  9. Huang CC, Lien HH, Tu SH, Huang CS, Jeng JY, Chao HL. Quality of life in Taiwanese breast cancer survivors with breast-conserving therapy. J Formos Med Assoc 2010; 109(7):493-502. doi: 10.1016/S0929-6646(10)60083-6 [Crossref]
  10. Kuo C, Liang S, Tsay S, Wang T-J. Symptom management tasks and behaviors related to chemotherapy in Taiwanese outpatients with breast cancer. European Journal of Oncology Nursing 2015; 19(6):654-9. doi: 10.1016/j.ejon.2015.03.012 [Crossref]
  11. Riegel B, Carlson B, Moser DK, Sebern M, Hicks FD, Roland V. Psychometric testing of the self-care of heart failure index. J Card Fail 2004; 10(4):350-60. doi: 10.1016/j.cardfail.2003.12.001 [Crossref]
  12. Dişsiz G, Yilmaz M. Complementary and alternative therapies and health literacy in cancer patients. Complementary therapies in clinical practice. Complement Ther Clin Pract 2016; 23:34-9. doi: 10.1016/j.ctcp.2016.02.004 [Crossref]
  13. Cordasco KM, Asch SM, Franco I, Mangione CM. Health literacy and english language comprehension among elderly inpatients at an urban safety-net hospital. J Health Hum Serv Adm 2009; 32(1):30-50.
  14. Halbach SM, Enders A, Kowalski C, Pförtner T-K, Pfaff H, Wesselmann S. Health literacy and fear of cancer progression in elderly women newly diagnosed with breast cancer—a longitudinal analysis. Patient Educ Couns 2016; 99(5):855-62. doi: 10.1016/j.pec.2015.12.012 [Crossref]
  15. Haghdoost AA, Rakhshani F, Aarabi M, Montazeri A. Iranian Health Literacy Questionnaire (IHLQ): an instrument for measuring health literacy in Iran. Iran Red Crescent Med J 2015; 17(5):258-66. doi: 10.5812/ircmj.17(5)2015.25831 [Crossref]
  16. Coolbrandt A, Koen Van den H, Kathleen C, Koen M, Annousch k, Hans W. The leuven questionnaire for patient self-care during chemotherapy (L-PaSC): instrument development and psychometric evaluation. European Eur J Oncol Nurs 2013; 17(3):275-83. doi: 10.1016/j.ejon.2012.07.008 [Crossref]
  17. Prutipinyo C, Maikeow K, Sirichotiratana N. Self-care behaviours of chemotherapy patients. J Med Assoc Thai 2012; Suppl 6:30-7.
  18. U.S. Department of Health & Human Services. Chemotherapy and you: support for people with cancer [Internet][cited 25 Feb. 2019]. 1st ed. Bethesda: National Cancer Institute; 2011. Available from: https://www.cancer.gov/publications/patient-education/chemotherapy-and-you.pdf.
  19. Palme M, Simeonova E. Does women’s education affect breast cancer risk and survival? evidence from a population based social experiment in education. Journal of Health Economics 2015; 14:115-24. doi: 10.1016/j.jhealeco.2014.11.001 [Crossref]
  20. Hart TL, Blacker S, Panjwani A, Torbit L, Evans M. Development of multimedia informational tools for breast cancer patients with low levels of health literacy. Patient Educ Couns 2015; 98(3):370-7. doi: 10.1016/j.pec.2014.11.015 [Crossref]
  21. Sorensen L, Gavier M, Helles R. Latina breast cancer survivors informational needs: information partners. Stud Health Technol Inform 2009; 146:727.
  22. Halbach SM, Ernstmann N, Kowalski C, Pfaff H, Pförtner T-K, Wesselmann S. Unmet information needs and limited health literacy in newly diagnosed breast cancer patients over the course of cancer treatment. Patient Educ Couns 2016; 99(9):1511-8. doi: 10.1016/j.pec.2016.06.028 [Crossref]
  23. Ridner SH, Dietrich MS, Kidd N. Breast cancer treatment-related lymphedema self-care: education, practices, symptoms, and quality of life. Support Care Cancer 2011; 19(5):631-7. doi: 10.1007/s00520-010-0870-5 [Crossref]
  24. Hendrix CC, Bailey DE Jr, Steinhauser KE, Olsen MK, Stechuchak KM, Lowman SG. Effects of enhanced caregiver training program on cancer caregiver’s self-efficacy, preparedness, and psychological well-being. Support Care Cancer 2016; 24(1):327-36. doi: 10.1007/s00520-015-2797-3 [Crossref]
  25. Liang SY, Chao TC, Tseng LM, Tsay SL, Lin KC, Tung HH. Symptom-management self-efficacy mediates the effects of symptom distress on the quality of life among Taiwanese oncology outpatients with breast cancer. Cancer Nurs 2016; 39(1):67-73. doi: 10.1097/NCC.0000000000000244 [Crossref]
  26. Miaskowski C, Dodd M, West C, Schumacher K, Paul SM, Tripathy D. Randomized clinical trial of the effectiveness of a self-care intervention to improve cancer pain management. J Clin Oncol 2004; 22(9):1713-20. doi: 10.1200/JCO.2004.06.140 [Crossref]
  27. Lorig KR, Sobel DS, Stewart AL, Brown Jr BW, Bandura A, Ritter P. Evidence suggesting that a chronic disease self-management program can improve health status while reducing hospitalization: a randomized trial. Med Care 1999; 37(1):5-14. doi: 10.1097/00005650-199901000-00003 [Crossref]
  28. Haghighi F, Khodaei S, Sharifzadeh Gh.R. Effect of logotherapy group counseling on depression in breast cancer patients. Modern Care Journal 2012; 9(3):165-72.
  29. Davis TC, Williams MV, Marin E, Parker RM, Glass J. Health literacy and cancer communication. CA Cancer J Clin 2002; 52(3):134-49. doi: 10.3322/canjclin.52.3.134 [Crossref]
  30. Gazmararian JA, Williams MV, Peel J, Baker DW. Health literacy and knowledge of chronic disease. Patient Educ Couns 2003; 51(3):267-75. doi: 10.1016/s0738-3991(02)00239-2 [Crossref]
Submitted: 03 Oct 2018
Accepted: 06 Mar 2019
First published online: 01 Mar 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - FireFox Plugin)

Abstract View: 1395
PDF Download: 896
Full Text View: 333