Tabriz University of Medical Sciences Journal of Caring Sciences 2251-9920 14 2 2025 07 08 Effect of Activity Therapy on Self-Esteem among Patients with Schizophrenia: A Randomized Controlled Trial 80 85 10.34172/jcs.025.33341 EN Delmy Paul https://orcid.org/0009-0003-7623-9122 Rajendran Rangasamy Kavitha https://orcid.org/0000-0002-2660-0608 Moushumi Purkayastha Mukherjee https://orcid.org/0009-0006-2436-1072 KT Harichandrakumar https://orcid.org/0000-0002-8946-763X Journal Article 10.34172/jcs.025.33341 2024 01 27 2025 06 02 Introduction: Schizophrenia is a chronic mental disorder that adversely affects patients’ self-esteem. Activity therapy has been shown to positively influence self-esteem. This study aims to examine the efficacy of activity therapy in improving self-esteem among patients with schizophrenia. Methods: In this randomized controlled study, 79 patients diagnosed with schizophrenia were enrolled using a consecutive sampling technique. The participants were assigned into intervention (39 participants) and control groups (40 participants) using computer-generated randomization. Researchers used The Rosenberg Self-Esteem Scale (RSES) to assess the participants’ self-esteem. The intervention group underwent activity therapy of making bags and envelopes using paper for seven days. The control group received routine psychiatric care. The post-test assessment was done using RSES after 7 and 15 days of intervention. Data was analyzed using descriptive and inferential statistics using SPSS software version 21. Results: The total self-esteem score at both 7 days and 15 days post-intervention were significantly higher in the intervention group compared to the control group. Conclusion: Evidence suggests that structured manual activities, such as the fabrication of paper bags and envelopes, may contribute to enhanced self-esteem and greater self-efficacy in patients, thereby facilitating improved psychosocial functioning. However, additional rigorous research is required to substantiate these observations.