Tabriz University of Medical Sciences Journal of Caring Sciences 2251-9920 10 1 2021 03 01 Effectiveness of Self-care Measures on Knowledge, Self-efficacy and Performance Status among Cancer Patients 1 8 10.34172/jcs.2021.003 EN Vijayakrishnan Prathiba Sivakumar https://orcid.org/0000-0002-4766-0749 Chandrasekaran Susila Journal Article 10.34172/jcs.2021.003 2020 06 04 2020 07 24 Abstract Introduction:There is a growing concern regarding self-care and chemotherapy side effects. The present study aimed to assess the effectiveness of self-care measures on knowledge, self-efficacy, and performance status among cancer patients undergoing chemotherapy. Methods: A quasi-experimental study was conducted in Dr. Kamatchi Memorial Hospital, India. Using purposive sampling technique, 200 cancer patients were selected. Patients were interviewed using semi-structured knowledge questionnaires, Modified Stanford Patient Education Research Center Self-efficacy scale, deliberate self-efficacy with rating scale under four subheadings, and ECOG Performance Status Scale with 5–point grading scale i.e., dead to fully active. Results:There was adequate knowledge (95%) on self-care measures after the intervention. The mean score was significant, i.e., 21.33 (2.25), which had difference between post-knowledge score in experimental and control was statistically significant at P < 0.001 level. The majority of patients reported a high self-efficacy level (t = 198.60, P < 0.001). In addition, despite self-efficacy and knowledge the performance status observed at each cycle, i.e., 4 cycles had mean score of t = 32.13, P < 0.001, showed high level of performance status. Conclusion: The study revealed that the self-care measures during each cycle had improved the selfefficacy and performance status to high level, which in turn reduced the side effects of chemotherapy to the certain level.