Tabriz University of Medical Sciences Journal of Caring Sciences 2251-9920 14 4 2025 12 28 Resilience and Well-being among Indonesian Nurses in the Post-COVID-19 Era: A Cross-sectional Study 226 234 10.34172/jcs.025.33323 EN Hema Malini https://orcid.org/0000-0002-3224-5657 Rika Sarfika https://orcid.org/0000-0001-7066-568X Siska Mayang Sari https://orcid.org/0000-0001-8791-0688 I Made Moh Yanuar Saifudin https://orcid.org/0000-0002-1549-6403 Intan Yullya Kardila https://orcid.org/0009-0008-0136-8081 Hadeci Lovenda Putri https://orcid.org/0000-0003-2114-3951 Hikayati Hikayati https://orcid.org/0000-0003-4748-2417 Journal Article 10.34172/jcs.025.33323 2024 01 08 2025 10 05 Introduction: The COVID-19 pandemic has highlighted the strain on healthcare systems, notably in Indonesia. This study aimed to examine the resilience and psychological well-being of nurses working in local government hospitals in the post-COVID-19 period, providing insights into the specific challenges they face. Methods: A cross-sectional survey involving 567 nurses from eight public hospitals across Sumatra Island was conducted. Participants completed the 10-item Connor-Davidson Resilience Scale (CD-RISC-10) and an 18-item Psychological Well-Being questionnaire. Results: Nurses demonstrated high levels of resilience (93.8%) and good psychological well-being (85.9%). A positive correlation was found between resilience and psychological well-being (r=0.287, P<0.001). Resilience was significantly associated with chronic illness history and nursing experience, whereas age influenced the spiritual dimension of resilience and domains of purpose in life and self-acceptance in well-being. Conclusion: The findings suggest a need for tailored strategies, considering factors such as chronic illness, nursing tenure, and age, to enhance psychological well-being among nurses. Customized approaches for different age groups are recommended to support overall resilience and well-being.