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J Caring Sci. 2016;5(1): 67-73. doi: 10.15171/jcs.2016.007
PMID: 26989667        PMCID: PMC4794546

Original Research

Effect of Combined Use of Calcium and Vitamin B6 on Premenstrual Syndrome Symptoms: a Randomized Clinical Trial

Seyedeh Zahra Masoumi 1, Maryam Ataollahi 2 * , Khodayar Oshvandi 3

Cited by CrossRef: 16

1- Fathizadeh S, Amani R, Haghighizadeh M, Hormozi R. Comparison of serum zinc concentrations and body antioxidant status between young women with premenstrual syndrome and normal controls: A case-control study. IJRM. 2016;14(11):699 [Crossref]
2- Mahmood A, Fatima N, Rafaqat Z, Raza A, Shehzadi A. Impact of Premenstrual syndrome on quality of life of working women . PBMJ. 2022;:104 [Crossref]
3- Fradista A. Hubungan Tingkat Konsumsi Zat Gizi dan Tingkat Stres Psikologis dengan Kejadian Premenstrual Syndrome Pada Mahasiswi Indekos Usia 18–22 Tahun di Fakultas Farmasi Universitas Airlangga. MGK. 2023;12(1):94 [Crossref]
4- Sultana A, Heyat M, Rahman K, Kunnavil R, Fazmiya M, Akhtar F, Akhtar S, Vidal Mazón J, Rodríguez C, De La Torre Díez I. A Systematic Review and Meta-Analysis of Premenstrual Syndrome with Special Emphasis on Herbal Medicine and Nutritional Supplements. Pharmaceuticals. 2022;15(11):1371 [Crossref]
5- Shobeiri F, Araste F, Ebrahimi R, Jenabi E, Nazari M. Effect of calcium on premenstrual syndrome: A double-blind randomized clinical trial. Obstet Gynecol Sci. 2017;60(1):100 [Crossref]
6- Maskani S, Tafazoli M, Rakhshandeh H, Esmaily H. Effect of Nigella sativa seeds on the severity of symptoms of premenstrual syndrome: A randomized clinical trial. Koomesh. 2020;22(1):33 [Crossref]
7- Sultana A, Rahman K, Heyat M, Heyat S, Akhtar F, Muaad A, Kuo C. Role of Inflammation, Oxidative Stress, and Mitochondrial Changes in Premenstrual Psychosomatic Behavioral Symptoms with Anti-Inflammatory, Antioxidant Herbs, and Nutritional Supplements. Oxidative Medicine and Cellular Longevity. 2022;2022:1 [Crossref]
8- Pal R, Pal Y, Wal P, Saraswat N, Wal A. A Novel Approach on Review of Herbal Menstrual Cramps Relievers. CWHR. 2019;15(3):179 [Crossref]
9- Chen X, Lei T. Glycerol fructose combined with vitamin B6 is beneficial to postoperative recovery of patients with cerebral aneurysm. Exp Ther Med. 2018; [Crossref]
10- Lovkina O, Tarasiuk S, Muntyan O. Features of the use of combined oral contraceptives for the correction of premenstrual syndrome. Rep of Vinnytsia Nation Med Univ. 2025;29(1):142 [Crossref]
11- Heidari H, Amani R, Feizi A, Askari G, Kohan S, Tavasoli P. Vitamin D Supplementation for Premenstrual Syndrome-Related inflammation and antioxidant markers in students with vitamin D deficient: a randomized clinical trial. Sci Rep. 2019;9(1) [Crossref]
12- Ezadi Z, Ramozi M, Barati H, Hosseini M, Hakimi S, Mohammady N, Ozaki A, Kotera Y, Kaneda Y, Ramozi P, Bek B. Prevalence and Associated Factors of Premenstrual Syndrome Among Female University Students of the Reproductive Age Group in Kabul, Afghanistan: A Cross-Sectional Study. Women's Health Reports. 2025;6(1):403 [Crossref]
13- Badihian S, Manouchehri N, Mirmosayyeb O, Ashtari F, Shaygannejad V. Neuromyelitis optica spectrum disorder and menstruation. Revue Neurologique. 2018;174(10):716 [Crossref]
14- Cherak S, Fiest K, VanderSluis L, Basualdo-Hammond C, Lorenzetti D, Buhler S, Stadnyk J, Driedger L, Hards L, Gramlich L, Fenton T. Nutrition interventions in populations with mental health conditions: a scoping review. Appl Physiol Nutr Metab. 2020;45(7):687 [Crossref]
15- Lee A. The Role of Vitamin B6 in Women’s Health. Nursing Clinics of North America. 2021;56(1):23 [Crossref]
16- Mirmosayyeb O, Badihian S, Manouchehri N, Basiri A, Barzegar M, Esmaeil N, Fayyazi E, Shaygannejad V. The interplay of multiple sclerosis and menstrual cycle: Which one affects the other one?. Multiple Sclerosis and Related Disorders. 2018;21:46 [Crossref]
17- Arab A, Rafie N, Askari G, Taghiabadi M. Beneficial role of calcium in premenstrual syndrome: A systematic review of current literature. Int J Prev Med. 2020;11(1):156 [Crossref]
18- İlçioğlu K, Yıldırım Bayraktar B, Demirhan Kayacık A. The Effect of Calcium on Premenstrual Syndrome: A Meta-Analysis Study. J CLIN MED KAZ. 2025;22(1):43 [Crossref]