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J Caring Sci. 2019;8(3): 181-189. doi: 10.15171/jcs.2019.026
PMID: 31598511        PMCID: PMC6778311

Original Research

Effect of the Mixed Herbal Medicines Extract (Fennel, Chamomile, and Saffron) on Menopause Syndrome: a Randomized Controlled Clinical Trial

Mitra Mahdavian 1 ORCID, Khadijeh Mirzaii Najmabadi 1 * ORCID, Hossein Hosseinzadeh 2 ORCID, Sara Mirzaeian 3 ORCID, Shapour Badiee Aval 4 ORCID, Habibollah Esmaeeli 2 ORCID

Cited by CrossRef: 8


1- He Q, Zhong Z, Liu M, Tong Z, Wu Q, Chen M. Efficacy and Safety of Acupuncture Vs. Hormone Therapy for Menopausal Syndrome: A Systematic Review and Meta-Analysis. Am J Chin Med. 2021;49(08):1793 [Crossref]
2- Lopresti A, Smith S. The Effects of a Saffron Extract (affron®) on Menopausal Symptoms in Women during Perimenopause: A Randomised, Double-Blind, Placebo-Controlled Study. J Menopausal Med. 2021;27(2):66 [Crossref]
3- Koliji T, Keshavarz Z, Mojab F, Nasiri M, Zare E. Comparison of Cinnamon and Vitex on Improving Sexual Function in Postmenopausal Women: A Triple-blind Randomized Clinical Trial. Jundishapur J Nat Pharm Prod. 2022;17(4) [Crossref]
4- Liu X, Wang Z, Song X, Chang X, Zu E, Ma X, Sukegawa M, Liu D, Wang D. Crocetin Alleviates Ovariectomy-Induced Metabolic Dysfunction through Regulating Estrogen Receptor β. J Agric Food Chem. 2021;69(49):14824 [Crossref]
5- Irani M, Rahmanian A, Soltani N. Efficacy of Saffron (Crocus sativus L.) in Premenstrual Syndrome, Labor, Childbirth, and Menopause: A Systematic Review of Clinical Trials. Mod Care J. 2023;20(3) [Crossref]
6- Costa S, Domingues T, Rodrigues C, Silva S, Diniz e Magalhães C, Costa-Pereira L, Peixoto M, da Fonseca S, Sampaio K, Mendonça V, Lacerda A. Does endurance training prior to ovariectomy protect against myocardial contractility dysfunction in rats?. Experimental Gerontology. 2021;155:111556 [Crossref]
7- Silva E, Dos Santos F, Marinheiro H, De Amorim R, Cavalcante T, De Almeida R, Coêlho P, Dos Santos E, Figueiredo S. O USO DE PLANTAS MEDICINAIS POR MULHERES NA ATENÇÃO BÁSICA PARA AMENIZAR SINTOMAS DO CLIMATÉRIO: REVISÃO INTEGRATIVA DA LITERATURA. Rev Contemp. 2023;3(12):31089 [Crossref]
8- Ahn J, Kim H, Damodar K, Shin H, Kim K, Park J, Jang S, Yoo Y, Jung J, Joo S. Styphnolobium japonicum Fruit and Germinated Soybean Embryo Complex Extract for Postmenopausal-Symptom Relief. Nutrients. 2024;16(19):3297 [Crossref]
9- Abdi F, Rahnemaei F, Roozbeh N, Pakzad R. Impact of phytoestrogens on treatment of urogenital menopause symptoms: A systematic review of randomized clinical trials. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2021;261:222 [Crossref]
10- Davydova Y, Lymanska A, Dvulit M, Fedorova N. The role of non-hormonal methods in treatment of urogenital menopausal syndrome: modern views . RHW. 2021;(9-10):17 [Crossref]